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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LACTB All Species: 18.18
Human Site: S218 Identified Species: 44.44
UniProt: P83111 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P83111 NP_116246.2 547 60694 S218 R L L I S H L S G I R H Y E K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001104610 547 60609 S218 R L L I S H L S G I R H Y E K
Dog Lupus familis XP_544713 464 52180 K141 E K D M K K V K E E K A Y K A
Cat Felis silvestris
Mouse Mus musculus Q9EP89 551 60687 S216 R L L I S H L S G I R H Y E K
Rat Rattus norvegicus NP_001100303 550 60402 S216 R L L I S H L S G I R H Y E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518282 438 49452 K115 I K K V K E E K A L K G L R M
Chicken Gallus gallus NP_001025717 520 57986 S176 R L L V S H L S G I R H Y E K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001018429 536 60352 M209 N V T I T P R M L L S H L S G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_001041033 407 44448 K84 A N L E S F A K C T G D S V M
Sea Urchin Strong. purpuratus XP_789736 431 48634 Q108 K E A D E D N Q K D N S N K H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 98.1 76.2 N.A. 88 87 N.A. 64.9 66.9 N.A. 51.7 N.A. N.A. N.A. 30.1 34
Protein Similarity: 100 N.A. 98.5 79.5 N.A. 92 90.9 N.A. 72 76.5 N.A. 67.2 N.A. N.A. N.A. 44.6 49.3
P-Site Identity: 100 N.A. 100 6.6 N.A. 100 100 N.A. 0 93.3 N.A. 13.3 N.A. N.A. N.A. 13.3 0
P-Site Similarity: 100 N.A. 100 33.3 N.A. 100 100 N.A. 20 100 N.A. 33.3 N.A. N.A. N.A. 13.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 10 0 10 0 0 10 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % C
% Asp: 0 0 10 10 0 10 0 0 0 10 0 10 0 0 0 % D
% Glu: 10 10 0 10 10 10 10 0 10 10 0 0 0 50 0 % E
% Phe: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 50 0 10 10 0 0 10 % G
% His: 0 0 0 0 0 50 0 0 0 0 0 60 0 0 10 % H
% Ile: 10 0 0 50 0 0 0 0 0 50 0 0 0 0 0 % I
% Lys: 10 20 10 0 20 10 0 30 10 0 20 0 0 20 50 % K
% Leu: 0 50 60 0 0 0 50 0 10 20 0 0 20 0 0 % L
% Met: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 20 % M
% Asn: 10 10 0 0 0 0 10 0 0 0 10 0 10 0 0 % N
% Pro: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 50 0 0 0 0 0 10 0 0 0 50 0 0 10 0 % R
% Ser: 0 0 0 0 60 0 0 50 0 0 10 10 10 10 0 % S
% Thr: 0 0 10 0 10 0 0 0 0 10 0 0 0 0 0 % T
% Val: 0 10 0 20 0 0 10 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 60 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _